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Index > Protein center > TIMM9(Gene name) > Human
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  • TIMM9 (Gene name),
  • Mitochondrial import inner membrane translocase subunit Tim9 (Protein name ),  TIM9_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TIMM9(TIM9;TIM9A;TIMM9A);
    Protein name:
    Mitochondrial import inner membrane translocase subunit Tim9;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterohexamer; composed of 3 copies of TIMM9 and 3 copies of TIMM10/TIM10A, named soluble 70 kDa complex. The complex forms a 6-bladed alpha-propeller structure and associates with the TIMM22 component of the TIM22 complex. Interacts with multi-pass transmembrane proteins in transit. Also forms a complex composed of TIMM9, TIMM10/TIM10A and FXC1/TIM10B.
    Function:
    Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
    Subcellular Location:
    Mitochondrion inner membrane Peripheral membrane protein Intermembrane side
    Protein Attributes:
    Sequence length:
    89
    Sequence:
    50:
    MAAQIPESDQ | IKQFKEFLGT | YNKLTETCFL | DCVKDFTTRE | VKPEETTCSE | 
    89:
    HCLQKYLKMT | QRISMRFQEY | HIQQNEALAA | KAGLLGQPR
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    String:
    MIM:
    UniGene:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    E3445h
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    ELISA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    ELISA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    ELISA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    ELISA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    CLIA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    U3445c
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    96T
    CLIA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    CLIA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    CLIA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    CLIA Kit for Human Mitochondrial import inner membrane translocase subunit Tim9
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    Polyclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
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    P3445Rb-r
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    Polyclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
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    P3445Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Polyclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
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    P3445Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Monoclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Monoclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Monoclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Monoclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Monoclonal Antibody for Human Mitochondrial import inner membrane translocase subunit Tim9
    Protein for Human Mitochondrial import inner membrane translocase subunit Tim9
    Protein for Human Mitochondrial import inner membrane translocase subunit Tim9
    Protein for Human Mitochondrial import inner membrane translocase subunit Tim9
    Protein for Human Mitochondrial import inner membrane translocase subunit Tim9
    Protein for Human Mitochondrial import inner membrane translocase subunit Tim9

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    References
    1. 1.
      "The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom."
      Bauer M.F. , Rothbauer U. , Muehlenbein N. , Smith R.J.H. , Gerbitz K.-D. , Neupert W. , Brunner M. , Hofmann S.
      FEBS Lett.464:41-47(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    2. 2.
      "The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins."
      Jin H. , Kendall E. , Freeman T.C. , Roberts R.G. , Vetrie D.L.P.
      Genomics61:259-267(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Hippocampus.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
      tissue: Skin.
    6. 6.
      "Role of the deafness dystonia peptide 1 (DDP1) in import of human Tim23 into the inner membrane of mitochondria."
      Rothbauer U. , Hofmann S. , Muehlenbein N. , Paschen S.A. , Gerbitz K.-D. , Neupert W. , Brunner M. , Bauer M.F.
      J. Biol. Chem.276:37327-37334(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    7. 7.
      "Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria."
      Muehlenbein N. , Hofmann S. , Rothbauer U. , Bauer M.F.
      J. Biol. Chem.279:13540-13546(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH TIMM10; TIMM22 AND FXC1
    8. 8.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller."
      Webb C.T. , Gorman M.A. , Lazarou M. , Ryan M.T. , Gulbis J.M.
      Mol. Cell21:123-133(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) IN COMPLEX WITH TIMM10;DISULFIDE BONDS
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